Magento 2 Change Core Config Value Programmatically

$objectManager = \Magento\Framework\App\ObjectManager::getInstance(); // Instance of object manager

$cacheTypeList = $objectManager->get('\Magento\Framework\App\Cache\TypeListInterface');
$cacheFrontendPool = $objectManager->get('\Magento\Framework\App\Cache\Frontend\Pool');

$resource = $objectManager->get('Magento\Framework\App\ResourceConnection');
$connection = $resource->getConnection();
$table = $resource->getTableName('core_config_data'); 
$select = $connection->select()->from(
  $table,
  ['config_id', 'value']
 )->where(
  'path = ?',
  'carriers/storepickup/active'
 );

$data = $connection->fetchAll($select);
if ($data) {
 try {
  $connection->beginTransaction();

  foreach ($data as $value) {
   if($storeId == 1){
    $dvalue = !(bool)1; 
   }else{
    $dvalue = 1;
   }
   $bind = ['path' => 'carriers/storepickup/active', 'value' => $dvalue];
   $where = 'config_id = ' . $value['config_id'];
   $connection->update($table, $bind, $where);
  }

  $connection->commit();
  $types = array('config','layout','block_html','collections','reflection','db_ddl','eav',
    'config_integration','config_integration_api','full_page','translate','config_webservice');
  foreach ($types as $type) {
   $cacheTypeList->cleanType($type);
  }
  foreach ($cacheFrontendPool  as $cacheFrontend) {
   $cacheFrontend->getBackend()->clean();
  }
 } catch (\Exception $e) {
  $connection->rollback();
  throw $e;
 }
}